In this special episode on Residual Risk: A Focus on Triglycerides, our host, Dr. Neil Skolnik will discuss Residual Risk, Triglycerides and how to reduce residual risk with Dr. Charles Vega, Clinical Professor of Family Medicine and Associate Dean in the School of Medicine at the University of California, Irvine.

This special episode is supported by an independent educational grant from Amarin.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Charles Vega, M.D., Clinical Professor of Family Medicine, Director, UC Irvine Program in Medical Education for the Latino Community, and Associate Dean in the School of Medicine at the University of California, Irvine.

Selected references referred to the in the Podcast:

Icosapent Ethyl: REDUCE-IT - N Engl J Med 2019; 380:11-22

ADA Standards of Care: Diabetes Care 2023;46(Supplement_1):S158–S190

2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: Circulation. 2023;148. doi: 10.1161/CIR.0000000000001168

See Episode 1 for further references.

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update   discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

Welcome to diabetes core update where every month we go over the most important articles to come out in the field of diabetes. Articles that are important for practicing clinicians to understand to stay up with the rapid changes in the field. 

This issue will review:

1.     Association between changes in carbohydrate intake and long term weight changes

2.     Once-Weekly Insulin Icodec With Dosing Guide App Versus Once-Daily Basal Insulin Analogues in Insulin-Naive Type 2 Diabetes (ONWARDS 5)

3.     Achieving Normoglycemia With Tirzepatide: Analysis of SURPASS 1–4 Trials

4.     Tight Blood-Glucose Control without Early Parenteral Nutrition in the ICU The TGC-Fast study

5.     Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1)

For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org.

Hosts:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

In this second special episode on The Importance of Nutrient-Dense Diets, our host, Dr. Neil Skolnik will moderate further discussion with two experts about the role of nutrition in the prevention and management of diabetes and related complications, as well as challenges in implementing and sticking to healthy dietary strategies of some things we can do to help our patients adhere to a healthy diet.

This special edition of Diabetes Core Update is sponsored by Fresh Avocados - Love One Today.     For more information, as well as diabetes-friendly mean plans and a free downloadable toolkit just go to: www.Loveonetoday.com/diabetes   .

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Dr. Nikki Ford, PhD, Senior Director of the Avocado Nutrition Center.  

Elizabeth Hanna, MS, RDN, CDCES.

In this special episode on Diabetes in a Geriatric Population, our host, Dr. Neil Skolnik will discuss diabetes in a geriatric population with Dr. Medha Munshi, Director of the Joslin Geriatric Diabetes Program, focusing on deintensification of therapy.

This special episode is supported by an independent educational grant from Sanofi.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Medha Munshi, M.D.,   Director of the Joslin Geriatric Diabetes Program, Associate Professor of Medicine at Harvard Medical School

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update   discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

Welcome to diabetes core update where every month we go over the most important articles to come out in the field of diabetes. Articles that are important for practicing clinicians to understand to stay up with the rapid changes in the field.  I’m Dr, Neil Skolnik and …

This issue will review:

1.     Efficacy and safety of co-administered once-weekly cagrilintide 2·4 mg with once-weekly semaglutide 2·4 mg in type 2 diabetes: a multicentre, randomised, double-blind, active-controlled, phase 2 trial

2.     Association Between Diabetes Technology Use and Glycemic Outcomes in Adults With Type 1 Diabetes Over a Decade

3.     Efficacy and Safety of IDegLira Versus Basal- Bolus in Patients With Poorly Controlled Type 2 Diabetes and Very High HbA1c

4.      Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes

For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org.

Hosts:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

In this special episode on Residual Risk: A Focus on Triglycerides, our host, Dr. Neil Skolnik will discuss Residual Risk, Triglycerides and how to reduce residual risk with Dr. Christie Ballantyne, Director of the Center for Cardiometabolic Disease Prevention, Baylor College of Medicine.

This special episode is supported by an independent educational grant from Amarin.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Dr. Christie Ballantyne.  Dr. Ballantyne is a Professor of Medicine-Cardiology, and Director of the Center for Cardiometabolic Disease Prevention, Baylor College of Medicine.

Selected references in the Podcast:

Niacin: AIM-HIGH - N Engl J Med 2011; 365:2255-2267

Omega-3 Fatty Acids: STRENGTH trial - JAMA. 2020;324(22):2268-2280

Pemafibrate: PROMINENT - N Engl J Med 2022; 387:1923-1934

Icosapent Ethyl: JELIS - Lancet. 2007;369(9567):1090-1098

Icosapent Ethyl: REDUCE-IT - N Engl J Med 2019; 380:11-22

ADA Standards of Care: Diabetes Care 2023;46(Supplement_1):S158–S190

2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: Circulation. 2023;148. doi: 10.1161/CIR.0000000000001168

In this special episode on Diabetes in a Geriatric Population, our host, Dr. Neil Skolnik will discuss diabetes in a geriatric population with Dr. Medha Munshi, Director of the Joslin Geriatric Diabetes Program.

This special episode is supported by an independent educational grant from Sanofi.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Medha Munshi, M.D.,   Director of the Joslin Geriatric Diabetes Program, Associate Professor of Medicine at Harvard Medical School

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update     discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

This issue will review:

1.     Long-term Weekly Icodec versus Daily Glargine U100 in Type 2 Diabetes without Previous Insulin

2.     Triple – Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial

3.     Effects of Tirzepatide Versus Insulin Glargine on Cystatin C–Based Kidney Function

4.     Relationship Among Diabetes, Obesity, and Cardiovascular Disease Phenotypes Complications

5.    Tirzepatide Once Weekly for the Treatment of Obesity in People with Type 2 Diabetes (SURMOUNT-2): a Phase 3 Trial

For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

This issue:

1.     Long-term effect of intensive lifestyle intervention on cardiometabolic risk factors and microvascular complications in patients with diabetes in real-world clinical practice: a 10-year longitudinal study

2.     Comparison of seven popular structured dietary programmes and risk of mortality and major cardiovascular events in patients at increased cardiovascular risk: systematic review and network meta-analysis

3.     Beverage consumption and mortality among adults with type 2 diabetes: prospective cohort study

4.     Higher Severe Mental Illness and Type 2 Diabetes Outcomes and Complications

5.     High Prevalence of NASH and Advanced Fibrosis in Type 2 Diabetes: A Prospective Study of 330 Outpatients Undergoing Liver Biopsies for Elevated ALT

6.    COVID-19 to Blame? Trends of Incidence and Sex Ratio in Youth-Onset Type 2 Diabetes

For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update d     iscusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

This issue will review:

1.     Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients

2.     Cardiovascular and Renal Benefits of Novel Diabetes Drugs by Baseline Cardiovascular Risk: A Systematic Review

3.     Deintensifying Diabetes Medications for Older Adults With Type 2 Diabetes

4.     Higher Neighborhood Drivability Is Associated With a Higher Diabetes Risk in Younger Adults

5.     Quantifying the Relationship Between Physical Activity Energy Expenditure and Incident Type 2 Diabetes: A Prospective Cohort Study  

6.    Weekly Glycemic Control Over Multiple Decades and Dementia Risk in People With Type 2 Diabetes

For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

In this special episode of Diabetes Core Update, Dr. Neil Skolnik is joined by Nikki Ford, PhD, and Lizz Hanna, MS, RDN, CDCES, to discuss the importance of a nutrient-dense diet for diabetes management and risk reduction. Discussions center around the scientific evidence supporting nutrient-rich eating patterns, why nutrients like unsaturated fats and fiber are beneficial, how foods like fresh avocado can support positive health outcomes, and best practices and approaches for helping patients implement sustainable dietary changes.

Presented by:

Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Nikki Ford, PhD, Senior Director of Nutrition, Avocado Nutrition Center

Lizz Hanna, MS, RDN, CDCES, Director of Nutrition, American Diabetes Association^®

This special series is made possible by Fresh Avocados—Love One Today^®. Love One Today is a leading source of the healthiest reasons and tastiest ways to enjoy fresh avocados. A science-based resource, it provides turnkey solutions that make it easy for health care professionals to stay on top of the latest research and confidently recommend avocados. For more science-backed resources, research and recipes visit LoveOneToday.com/healthprofessionals.

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

This issue will review:

1.     Cardiovascular Safety in Type 2 Diabetes With Sulfonylureas as Second-Line Drugs

2.     Noninvasive Hypoglycemia Detection in People With Diabetes Using Smartwatch Data

3.     Trial of Hybrid Closed-Loop Control in Young Children with Type 1 Diabetes

4.     Safety and efficacy of an oral insulin (Capsulin) in patients with early-stage type 2 diabetes

5.     Once-Weekly Basal Insulin Fc Demonstrated Similar Glycemic Control to Once-Daily Insulin Degludec in Insulin-Naive Patients With Type 2 Diabetes: A Phase 2 Randomized Control Trial

6.     Recommended and Prevalent Use of Glucagon-like Peptide-1 Receptor Agonists and Sodium–Glucose Cotransporter-2 Inhibitors in a National Population-Based Sample

For more information about each of ADA’s science and medical journals, please visit:  www.diabetesjournals.org.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

This issue will review:

1.     Initiation of Continuous Glucose Monitoring Is Linked to Improved Glycemic Control and Fewer Clinical Events in Type 1 and Type 2 Diabetes   

2.     Trends in the Prevalence of Lean Diabetes Among U.S. Adults, 2015–2020

3.    Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes

4.     Low-Carbohydrate Diet Scores and Mortality Among Adults With Incident Type 2 Diabetes

5.     Trends in baseline HbA1c and body-mass index in randomized placebo-controlled trials of type 2 diabetes from 1987 to 2022

6.     Disentangling the role of marital status and quality on average glycemic levels among adults 50 years and older

For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

In this special episode on Low and No Calorie Sweeteners,  our host, Dr. Neil Skolnik will discuss with two experts the safety, efficacy and practical applications of Low and No Calorie Sweeteners.  

This special episode is supported by an independent educational grant  from Heartland Food Group, the maker of the Splenda Group of Products.  For more information just go to: www.splenda.com .

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Hope Warshaw RD, CDE, BC-ADM, registered dietitian and Certified Diabetes Care and Education Specialist. She is a past president of the American Association of Diabetes Educators and secretary of the Academy of Nutrition and Dietetics Foundation board.

Katherine Appleton, PhD,  Professor of Psychology at Bournemouth University. Dr. Appleton has published widely in the area of eating behavior, health, and well-being.  Important to today’s topic, she was a co-author on a systematic review and meta-analyses of intervention studies on the effects of low-calorie sweeteners on energy intake and body weight, published in the International Journal of Obesity in 2021.

In this special episode on Time in Range: Medication Management,  Dr. Joshua Neumiller joins our host, Dr. Neil Skolnik to discuss the ADA/EASD 2022 algorithm for selection of medications for hyperglycemic management and the effect of those medications on time in range.  This special episode is supported by independent educational grants from Abbot and LifeScan.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Dr. Joshua Neumiller, Vice Chair & Allen I. White Distinguished Associate Professor of Pharmacotherapy at the College of Pharmacy and Pharmaceutical Sciences at Washington State University

For more information about CGM and Time in Range, please go to: www.professional.diabetes.org/timeinrange  

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

This issue will review:

1.     Efficacy of Dapagliflozin by Baseline Diabetes Medications: A Prespecified Analysis From the DAPA-CKD Study 

2.     An Examination of Whether Diabetes Control and Treatments Are Associated With Change in Frailty Index Across 8 Years  

3.     Diabetes Obesity and Metabolism. =Semaglutide improves cardiometabolic risk factors in adults with overweight or obesity 

4.     Glucagon Prescribing and Costs Among U.S. Adults With Diabetes, 2011–2021 

5.     Two-Year Follow-up From the T1GER Study: Continued Off-Therapy Metabolic Improvements in Children and Young Adults With New-Onset T1D Treated With Golimumab and Characterization of Responders   

6.     Youth-onset type 2 diabetes: the epidemiology of an awakening epidemic  

For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

In this special podcast we will focus on the changes in recommendations for CV Risk Reduction published in the 2023 American Diabetes Association’s Standards of Care.

The report is available at:  

https://professional.diabetes.org/content-page/practice-guidelines-resources   

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Robert A. Gabbay, MD, PhD, Chief Science and Medical Officer, American Diabetes Association

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

This issue will review:

1. Dietary factors and all-cause mortality in individuals with type 2 diabetes
2. Prevalence and Predictors of Household Food Insecurity and Supplemental Nutrition Assistance Program Use in Youth and Young Adults With Diabetes
3. Association of Sodium–Glucose Cotransporter-2 Inhibitors with Time to Dementia
4. Concomitant Use of Sulfonylureas and beta-Blockers with the Risk of Severe Hypoglycemia Among Patients With Type 2 Diabetes
5. A novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: A Phase 1b Trial
6. Different Types of Industry- Produced and Ruminant Trans Fatty Acid Intake and Risk of Type 2 Diabetes

For more information about each of ADA’s science and medical journals, please visitwww.diabetesjournals.org.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health